You cannot see, smell, or taste Naegleria fowleri, so the safest approach is to assume it could be present any time you are in warm fresh water and take the same simple steps every time. The single thing that matters most: keep warm fresh water from going up your nose.
In warm fresh water
- Hold your nose shut or wear a nose clip when jumping or diving into warm fresh water.
- Keep your head above water in hot springs and other untreated geothermal water.
- Avoid stirring up or digging in the sediment in shallow, warm fresh water — the ameba is more likely to live there.
- Take extra care during hot spells, when water is warmer and lower — the conditions the ameba likes best.
When rinsing your sinuses
- Use distilled or sterile water for sinus rinses, neti pots, and nasal cleansing.
- If you use tap water, boil it first and let it cool before rinsing.
- Never rinse your sinuses with untreated tap water straight from the faucet.
Warning signs
Early symptoms usually begin about 5 days after exposure, but can appear anywhere from 1 to 12 days. Once symptoms start, PAM progresses very quickly — death typically occurs about 5 days after symptoms begin, with a reported range of 1 to 18 days.
Early symptoms
- Headache
- Fever
- Nausea
- Vomiting
As it progresses
- Stiff neck
- Confusion
- Loss of balance
- Inattention to people and surroundings
- Seizures
- Hallucinations
- Coma
Get help right away
Get medical care right away if you suddenly develop fever, headache, vomiting, or a stiff neck — especially if you have recently been in warm fresh water. Tell the doctor about that exposure, or about any nasal rinsing, so they can consider this rare infection. Because PAM is so rare and moves so fast, saying it out loud can save time that matters.
Source: Medical and prevention information on this site is drawn from the U.S. Centers for Disease Control and Prevention (CDC). Always follow current CDC guidance and consult a medical professional. Information on this page reflects the CDC Naegleria fowleri pages reviewed on 2026-08-04.